Dixie Pyles, a PGY2 critical care pharmacy resident specializing in neurology, and Nick Kim, an emergency pharmacist and PGY2 resident, dive into the complexities of managing ARDS. They discuss the critical role of corticosteroids, exploring dosing strategies and the importance of timing in administration. Nick sheds light on the use of inhaled prostacyclins, highlighting their potential benefits in treatment. Together, they emphasize evidence-based practices and the evolving definitions of ARDS to enhance patient outcomes.