Dr. Colleen Brennan, an academic neonatologist at Washington University, shares her expertise on the critical first hours of a newborn’s life. She discusses recognizing respiratory distress, effective resuscitation techniques, and the challenges of neonatal transitions. Insights into the management of neonatal blood glucose levels are provided, along with the importance of monitoring oxygen after birth. She also reflects on balancing a medical career with motherhood, emphasizing the need for self-kindness in both personal and professional realms.