Swiss researchers Christoph Grani & Katja Odening discuss the assessment of risk stratification in hypertrophic cardiomyopathy (HCM) and the influence of genetics. They explore the role of genetic testing and late gadolinium enhancement (LGE) in diagnosing and visualizing fibrosis in HCM. The podcast also explores different approaches to quantifying LGE, the potential of AI-based segmentation, and the use of artificial intelligence for risk stratification and better patient outcomes.