Christine Pratt

Dr. Christine Pratt, an Associate Professor at the University of Ottawa, dives deep into the complexities of breast cancer research. She discusses her transition from endocrinology to focusing on NF-kappa B signaling and its implications for BRCA1-related proliferation mechanisms. Pratt highlights how estrogen influences gene expression and the repercussions of BRCA1 deficiency on DNA replication. She also shares insights on potential treatments like DMAPT to curb abnormal cell growth and the role of the RANK pathway in preventing tumors, making strides towards effective prophylactic strategies.