Chris Knight and Dr. Sandeep Basnet from Formation Bio share insights into the complex world of developing disease-modifying osteoarthritis drugs. They discuss the intricate challenges of clinical trials and drug discovery, emphasizing the importance of understanding disease mechanisms and patient variability. The potential impact of AI in enhancing drug development is explored, along with the exciting promise of emerging therapies that could revolutionize patient care and improve quality of life for those suffering from osteoarthritis.

Peter Spiegel, Amanda Chu, Jacopo Dettoni, and Chris Knight discuss the FT's ranking of best US cities for foreign investment. They explore Houston's rise as a top destination, Miami's drop in rankings, the role of talent and hybrid working, and factors contributing to high cost of living in certain cities.