Dr. Chi-yuan Hsu and Dr. Anthony Muiru discuss the relationship between acute kidney injury (AKI) and chronic kidney disease progression. They explore the impact of AKI on kidney function, the correlation between duration of obstruction and renal fibrosis, and the challenge of establishing an individual's baseline kidney function. They also highlight the importance of comprehensive data in studying CKD progression and distinguishing between AKI and CKD based on creatinine levels.