Dr. Judy Lieberman, a renowned pediatric professor at Harvard, and Dr. Caroline Junqueira, a visiting scientist and malaria expert from the Oswaldo Cruz Foundation, delve into the fascinating role of γδ T cells in combating Plasmodium infections. They discuss how these unique immune cells function against malaria, their evolution, and their implications for vaccine development. The conversation also touches on broader themes of immune responses, aging, and the intricate balance of inflammation in health and disease.