Dr. Caroline Andrew, an anesthesia resident at Massachusetts General Hospital, and Dr. David Nathan, Director of its Diabetes Center and Harvard Medical School Professor, delve into the complex relationship between intraoperative dexamethasone and diabetes. They discuss a case study highlighting elevated blood sugar risks, scrutinize a randomized control trial revealing dexamethasone’s significant impact on post-surgical glucose levels, and emphasize the importance of careful insulin management for diabetic patients, addressing the broader implications for patient outcomes.