Buddy Shah, the Managing Director of GiveWell, shares insights on evaluating charities for effective giving. He delves into the importance of evidence-based decision-making and the complexities of assessing long-term impacts in philanthropy. Shah discusses the significance of lobbying and R&D in achieving measurable outcomes. Also highlighted are challenges in addressing global health issues, like malaria prevention and air pollution. The conversation explores the balance between emotional engagement and data-driven strategies in effective altruism.