Bryan Den Hartog, an expert in foot and ankle surgery, discusses the complexities of post-operative pain from total ankle replacements. He highlights the critical challenges in diagnosis, emphasizing the need for comprehensive patient histories and advanced imaging techniques. The conversation touches on the comparison of revision rates among ankle, hip, and knee surgeries, revealing a pressing need for enhanced pain source identification. Den Hartog also shares insights on managing complications like infection and misalignment, giving a deeper understanding of this pervasive issue.