
Bruce Wittmann
Senior Applied Scientist at Microsoft with expertise in AI for protein design and synthetic biology, who helped build the red-teaming pipeline used in the Paraphrase Project.
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Oct 6, 2025 • 52min
Ideas: More AI-resilient biosecurity with the Paraphrase Project
Microsoft’s Eric Horvitz and guests Bruce Wittmann, Tessa Alexanian, and James Diggans discuss the Paraphrase Project—a red-teaming effort that exposed and secured a biosecurity vulnerability in AI-driven protein design. The work offers a model for addressing AI’s dual-use risks.Show notes