Nicholas Fabiano, a resident psychiatrist and mental health advocate, joins Brendon Stubbs, a distinguished researcher in exercise science, for an engaging discussion on treating depression. They explore how exercise can rival medications and therapy, revealing unique antidepressant mechanisms at play. The conversation highlights the importance of personalized exercise plans, the effectiveness of different modalities like aerobic training, and the necessity of enjoyment in physical activity. They also address the social aspects of exercise and its holistic benefits for mental health.