In this insightful discussion, Dr. Biykem Bozkurt, an expert in heart failure and a leading professor, joins internal medicine resident Dr. Hirsh Elhence and Dr. Mark Belkin, Co-Chair for a cardiology series. They delve into 2022 heart failure management guidelines, emphasizing effective screening for at-risk individuals. A case study highlights the importance of natriuretic peptide biomarkers. The trio discusses innovative strategies for screening high-risk patients and the shifting role of imaging and digital technologies in cardiac assessment.