Benjamin Schlechter

Senior physician in the Gastrointestinal Cancer Center at Dana-Farber/Harvard Medical School providing medical oncology perspective on TNT history, rationale, and systemic therapy sequencing.

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Nov 24, 2025 • 1h 5min

Journal Review in Colorectal Surgery: Total Neoadjuvant Therapy in Rectal Cancer

Join leading experts in the field as Benjamin Schlechter, a Senior Physician at Dana-Farber, dives into the evolution of Total Neoadjuvant Therapy (TNT) in rectal cancer treatment. Julio Garcia-Aguilar, from MSK, shares insights from the impactful OPRA trial on organ preservation strategies. Emmanouil Fokas reveals findings from German trials on radiation scheduling. They explore benefits of preoperative chemotherapy, survival outcomes, and how emerging trials and research are shaping future treatment options.

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