Patrick D. McGorry, MD, PhD, and Barnaby Nelson, PhD, discuss a sequential adaptive intervention strategy to target remission and functional recovery in young people at high risk of psychosis. They explore terminology, psychosocial interventions, challenges in clinical studies, and the importance of personalized care. They also discuss treatment effectiveness, low adherence to antidepressants, virtual reality, ongoing studies, and the need for uncovering new mechanisms for better patient care.
