Arnoud (Aernoud) Fiolet

Dr. Arnoud Fiolet, a cardiologist and researcher at Utrecht University, dives into his groundbreaking work on colchicine and its impact on coronary artery inflammation. He discusses the LoDoCo2 trial, revealing how colchicine reduces major adverse cardiovascular events by about 25%. The conversation highlights how colchicine affects plaque composition through imaging, leading to greater plaque calcification. Arnoud addresses study limitations and emphasizes the need for further research to explore the drug's mechanisms—promising insights into heart disease management.