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Arjun K. Manrai

PhD from the Department of Biomedical Informatics at Harvard Medical School. Co-author of a study comparing open-source and proprietary LLMs for complex diagnoses.

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Apr 4, 2025 • 18min

Can Open-Source LLMs Compete With Proprietary Ones for Complex Diagnoses?

Arjun K. Manrai, PhD, from Harvard Medical School, joins the discussion on the capabilities of open-source large language models (LLMs) versus proprietary ones for complex medical diagnoses. They delve into a recent study revealing that models like Meta's LLaMA 3.1 can match GPT-4's diagnostic abilities, challenging the notion of proprietary superiority. The conversation also highlights the benefits of privacy and accessibility in healthcare, and the vital role of AI chatbots in supporting physicians while underscoring the need for human oversight.