Ardem Patapoutian, a 2021 Nobel Laureate in Physiology or Medicine, shares his inspiring journey from delivering pizzas to groundbreaking discoveries in somatosensory neurons. He discusses the explosive impact of his findings on Piezo touch and pressure-sensing ion channels across physiology. Ardem reflects on the importance of immigrant contributions to science and navigates the challenges of newfound recognition while staying committed to research. With a dash of humor, he shares a unique tattoo linked to his discoveries, showcasing the personal side of scientific achievement.