Across biotech labs, researchers swim in oceans of process data: sensor streams, run records, engineering logs, and still, crucial decisions get stuck in spreadsheets or scribbled into fading notebooks. The challenge isn’t having enough information, it's knowing which actions actually move the needle in cell culture productivity, process stability, and faster timelines.

This episode, David Brühlmann brings on Ilya Burkov, Global Head of Healthcare and Life Sciences Growth at Nebius AI. With a career spanning NHS medicine, regenerative research, and cloud infrastructure, Ilya Burkov has lived the leap from microscope to server room. He’s seen firsthand how digital twins, autonomous experimentation, and cloud-first strategies are shifting the way biologics are developed and scaled.

Topics discussed:

Shifting from experimental-based to computational bioprocess development, and the evolving role of human expertise vs. AI (02:48)
Ilya Burkov's journey from medicine and orthopedics to AI and cloud infrastructure (04:15)
Solving data silos and making real-time decisions with digital twins and automated analytics (06:36)
The impact of AI-driven lab automation and robotics on drug discovery timelines (08:51)
Using AI to accelerate cell line selection, cloning, and protein sequence optimization (10:12)
Why wet lab experimentation is still essential, and how predictive modelling can reduce failure rates (11:15)
Reducing costs and accelerating development by leveraging AI in process screening and optimization (12:32)
Strategies for smaller companies to effectively store and manage bioprocess data, including practical advice on cloud adoption and security (14:30)
Application of AI and digital twins in scale-up processes, and connecting diverse data types like CFD simulations and process data (17:18)
The ongoing need for human expertise in interpreting and qualifying data, even as machine learning advances (19:09)

Wondering how to stop your own data from gathering dust? This episode unpacks practical strategies for storing and leveraging your experimental records - whether you’re in a major pharma or a small startup with limited tech resources.

Connect with Ilya Burkov:

LinkedIn: www.linkedin.com/in/ilyaburkov

Contact email: ilya.burkov@nebius.com

Nebius: www.nebius.com

If this topic grabbed you, you'll love these related episodes focusing on advanced modeling, continuous manufacturing, and Digital Twins

Episodes 213 - 214: From Developability to Formulation: How In Silico Methods Predict Stability Issues Before the Lab with Giuseppe Licari
Episodes 85 - 86: Bioprocess 4.0: Integrated Continuous Biomanufacturing with Massimo Morbidelli
Episodes 05 - 06: Hybrid Modeling: The Key to Smarter Bioprocessing with Michael Sokolov
Episode 153 - 154: The Future of Bioprocessing: Industry 4.0, Digital Twins, and Continuous Manufacturing Strategies with Tiago Matos
Episodes 173 - 174: Mastering Hybrid Model Digital Twins: From Lab Scale to Commercial Bioprocessing with Krist Gernaey

Next step:

Need fast CMC guidance? → Get rapid CMC decision support here

Support the show

Antonia Hodgson

The AI-powered Podcast Player