Greg Kirshen, a maternal-fetal medicine specialist, and Bobby Brar, a fellow in maternal-fetal medicine and clinical genetics, join Anna Jarvis, an OB/GYN resident, to discuss a complex case involving a 10-week pregnant woman with severe abdominal pain and large-volume ascites. They explore differential diagnoses, including infection and malignancy, and share insights on management strategies. The conversation emphasizes the importance of a broad differential and offers practical counseling for future pregnancies.