Amy Nordrum, the executive editor at MIT Technology Review, discusses the annual '10 Breakthrough Technologies' list. She highlights the challenges of distinguishing true innovations from fleeting trends. Topics include the game-changing Vera Rubin Telescope in Chile and its community collaborations. The conversation also covers revolutionary methane reduction technologies for cattle, as well as promising advancements in long-acting HIV medications and green steel production. Nordrum emphasizes how these developments could significantly impact health and the environment by 2025.