Alonzo Mourning, a two-time NBA champion noted for his defensive skills, joins Oscar Robertson, a groundbreaking player and social justice advocate, along with Dominique Wilkins, famed for his airborne theatrics. They reflect on the NBA's evolution, addressing global influences and the rise of international talent. Humorous college stories surface, alongside fierce rivalries highlighted by jaw-dropping dunks. They share poignant insights on athlete activism, resilience, and the community's role in shaping their identities and careers.

NBA great Alonzo Mourning recounts his fight against kidney disease and discusses breakthroughs in genetic research, the role of the APOL1 protein in preventing African sleeping sickness and its link to kidney disease, and Vertex Pharmaceuticals' groundbreaking research and efforts to develop transformative therapies.