In a thought-provoking discussion, Jamie Metzl, a technology and healthcare futurist, advocates for regulated germline editing, highlighting potential benefits. O. Carter Snead, a bioethicist, argues against such interventions, emphasizing parental humility and societal risks. Dr. Allyson Berent shares her personal experience with her daughter's condition, making a compelling case for editing to prevent suffering. Dr. Lydia Dugdale raises alarms about safety and the historical implications of eugenics, urging for cautious conversation on this emerging technology.