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Alexander Drilon
Chief of the Early Drug Development Service at Memorial Sloan Kettering Cancer Center and expert in targeted therapies for lung cancer; featured guest discussing the ARROS-1 trial of zidesamtinib for ROS1+ NSCLC.
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Sep 18, 2025
• 8min
S14 Ep19: Zidesamtinib Is Associated With CNS Activity and Low Rates of Neurologic AEs in Pretreated ROS1+ NSCLC: With Alexander Drilon, MD
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In this discussion, Dr. Alexander Drilon, a lung cancer expert from Memorial Sloan Kettering Cancer Center, dives into the ARROS-1 trial of zidesamtinib for ROS1-positive non-small cell lung cancer. He highlights the promising efficacy data, noting the drug's high central nervous system response rates and low neurological side effects. Dr. Drilon explores zidesamtinib's unique mechanism and its potential to redefine first-line treatment, especially for patients resistant to prior TKI therapies. His insights underscore zidesamtinib’s promising role in advancing lung cancer therapy.
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