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Alex Weiler
Emergency Department staff physician and associate professor in family medicine, serving as the guest skeptic presenting and discussing the TRAIN transfusion trial and its implications for acute brain injury care.
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Nov 16, 2025
• 18min
SGEM#492: Give Blood – To Anemic Patients with Acute Brain Injuries
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Dr. Alex Weiler, an Emergency Department physician and associate professor, dives into the TRAIN transfusion trial, exploring its significant findings for anemic patients with acute brain injuries. He discusses the trial's impact on transfusion thresholds and the effects on cerebral oxygenation. With a focus on how a liberal transfusion strategy can improve neurological outcomes, Alex evaluates biases in the study design. He also provides practical guidance for clinicians in managing these critical patients, emphasizing communication with families about treatment benefits.
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