Miriam Barshak, an infectious disease consultant at Massachusetts General Hospital, and Akash Gupta, a clinical assistant professor at the University of Pittsburgh Medical Center, delve deep into ocular infections. They discuss the crucial interplay between infectious disease specialists and ophthalmologists, emphasizing effective communication. Insights into ocular anatomy reveal how inflammation causes conditions like scleritis and keratitis. The duo shares intriguing case studies on ocular toxoplasmosis and syphilis, highlighting the importance of swift diagnosis and treatment to prevent vision loss.