Dr. Aaron Skolnick, an Assistant Professor at Mayo Clinic specializing in emergency medicine, dives into the complexities of diagnosing sepsis. He discusses the promising potential of Monocyte Distribution Width (MDW) as a rapid biomarker for early detection. Skolnick highlights the challenges of identifying sepsis due to its nonspecific symptoms and critiques existing diagnostic methodologies. The conversation also covers the biases in observational studies versus randomized control trials, and evaluates the clinical implications of MDW in emergency settings.

Dr. Aaron Skolnik, an Assistant Professor at Mayo Clinic and critical care expert, dives into the complexities of diagnosing sepsis. He highlights a critical case of a 62-year-old man with severe symptoms and discusses the limitations of current biomarkers. The conversation centers on monocyte distribution width (MDW) as a promising but not yet routine diagnostic tool for sepsis in emergency settings. Skolnik also examines biases in sepsis studies, underscoring the importance of clinician judgment in making accurate diagnoses.