Health & Veritas Alexi Nazem: Building Healthcare Solutions
Apr 3, 2025
In this discussion, physician-entrepreneur Alexi Nazem shares insights from his journey co-founding Nomad Health and now investing in healthcare at AlleyCorp. He recounts how his Yale experience and mentors shaped his approach to healthcare improvement. Alexi highlights pressing challenges in healthcare quality measurement and reflects on the pandemic's dual impact on staffing. He also delves into the potential of AI in healthcare, emphasizing caution in investment strategies and the need for innovative solutions in a rapidly changing landscape.
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Semaglutide Shows Vascular Benefits
- Semaglutide improved walking distance and limb perfusion in people with peripheral artery disease regardless of obesity status.
- Harlan suggests these GLP-1 drugs are moving from weight drugs to broader vascular and cardiometabolic therapies.
Long-Held Practices Were Challenged
- Randomized trials at ACC questioned long-standing practices like intra-aortic balloon pumps in cardiogenic shock and full-dose anticoagulation in cancer-associated clots.
- These trials showed no benefit for the pump and supported reduced-dose anticoagulation with fewer bleeds.
Working With Don Berwick Shaped His Path
- Alexi recounted meeting Don Berwick and accepting a role as his special assistant at IHI early in his career.
- That close work accelerated Alexi's education in systems improvement and shifted his career toward care delivery.