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SIBO Is Usually Multi-Factorial
- SIBO usually arises from a confluence of factors rather than a single cause.
- Dr. Will Cole emphasizes epigenetics and lifestyle as bigger drivers than genetics for most cases.
Limit Chronic NSAID Use
- Avoid chronic NSAID use where possible because they increase gut permeability.
- Dr. Will Cole recommends evaluating NSAID impact as part of gut-healing plans.
Begin With Gentle Dietary Foundations
- Start SIBO care with dietary foundation before aggressive treatments.
- Use gentler food strategies like broths, soups, and modified GAPS/AIP approaches to calm symptoms first.


