Understanding Chronic Hyperkalemia in CKD

Chronic hyperkalemia often arises from kidney dysfunction where the body's ability to excrete potassium is compromised. A patient with chronic kidney disease (CKD) and conditions like focal segmental glomerulosclerosis (FSGS) experiences elevated potassium levels due to reduced glomerular filtration rate (GFR) and impaired renal tubular function. This situation highlights the physician's need to remain calm while monitoring potassium levels, as long-term elevation is linked to issues with kidney function rather than acute cardiac risks. Important factors contributing to hyperkalemia in CKD patients can include medications like RAAS inhibitors, potassium-sparing diuretics, and certain immunosuppressants that further limit potassium excretion.