Recorded live in front of a sold out crowd at the Ryman Auditorium in Nashville on September 18, 2025, Kacey Musgraves and pioneering mycologist Paul Stamets dive deep into the biology, evolution, and mental health potential of psilocybin. From its ancient ritual roots to its emerging role in modern therapy, their conversation reveals how this once-taboo organism is transforming our understanding of consciousness, creativity, and healing. Along the way, they wander through unexpected terrain—spirituality, pandemics, AI, bees, dogs on mushrooms, and more—in a mind-expanding exploration of the heart of the woods.