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Business Of Biotech

Art Of The Pivot with Elevation Oncology's Joe Ferra

Jan 8, 2024
In this episode, the relatively new CEO of Elevation Oncology, Joseph Ferra, discusses the significant changes he has made at the company. These changes include transitioning from a monoclonal antibody candidate to a phase 1 Claudin18.2 target in the ADC space. The podcast also explores the importance of technology and being a platform company in the biotech industry, as well as the expansion of a clinical trial for gastric cancer treatment. Ferra emphasizes the need for planning and adaptability in the biotech industry to make the right decisions.
49:56

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Quick takeaways

  • Elevation Oncology's strategic portfolio moves, led by CEO Joe Farah, have positioned them as a leader in ADC development, focusing on stability, selectivity, and targeted delivery of therapeutic payloads.
  • Elevation Oncology's modality-agnostic approach and emphasis on partnerships enables them to maximize the potential impact of their drugs, utilizing various technologies and driving innovation in the crowded biotech landscape.

Deep dives

Elevation Oncology's Strategic Portfolio Moves: An Overview

Elevation Oncology has made significant strategic portfolio moves with its CEO and former CFO, Joe Farah, leading the way. With a focus on biologics process development and manufacturing challenges, Elevation Oncology has maneuvered its targeted ADC EO 3021 to phase one study status. The company's approach of embracing different technologies and evaluating the best options allows for flexibility and differentiation in the crowded biotech landscape. Elevation Oncology's ADC approach is rooted in the stability and selectivity of their molecules, showing promising results in their partnered phase one trial. The company has started enrolling patients in their own phase one trial and plans to expand internationally to treat gastric cancer, a high unmet need, leveraging the knowledge and expertise of their team. Elevation Oncology aims to be best in class and close to the first to class in developing drugs that can make a difference for patients.

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