OncoPharm Trimodality Treatment For Bladder Cancer
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May 18, 2023 Dive into the compelling discussion on trimodality treatment for muscle-invasive bladder cancer. Discover how combining surgical resection, chemotherapy, and radiation can preserve the bladder while weighing the pros and cons against radical cystectomy. The episode emphasizes the significance of personalized patient care and shared decision-making in crafting effective treatment plans.
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What Trimodality Means
- Trimodality combines surgery, radiation, and chemotherapy to treat muscle-invasive bladder cancer.
- Radical cystectomy remains the historical gold standard with neoadjuvant cisplatin commonly used beforehand.
Consequences Of Radical Cystectomy
- Radical cystectomy removes the entire bladder and often follows neoadjuvant cisplatin chemotherapy.
- Surgeons then create either an ileal conduit or a neobladder to manage urine after removal.
Offer Bladder Preservation When Appropriate
- Consider bladder-preserving trimodality to avoid cystectomy when appropriate and desired by the patient.
- Ensure maximal TURBT followed by chemosensitizing chemotherapy plus radiation for the best chance of organ preservation.