Science Fictions Episode 87: Does Tylenol cause autism?
Oct 14, 2025
Exploring the controversial claims linking Tylenol use in pregnancy to autism, the hosts delve into recent statements from public figures and health authorities. They discuss the implications of 'no evidence' in science communication and the pitfalls of confounding factors in studies. Various research findings, including sibling-control designs and ecological studies, shed light on the complexities of the data. They caution against misinterpretations while highlighting the necessity of balanced risk communication for expectant mothers.
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Personal Hospital Experience With IV Paracetamol
- Stuart Ritchie described receiving IV paracetamol in hospital for gallstone pain and finding it effective when morphine failed.
- He used this personal experience to note paracetamol can have real systemic effects despite a mild reputation.
FDA Warning Was Cautious But Alarmist In Practice
- The FDA warned there is a considerable body of evidence linking acetaminophen to potential neurodevelopmental risks but said causality isn't established.
- The statement's mixed tone and the presidential press conference made the issue seem bigger than the evidence warranted.
No Evidence Is A Red Flag For Communication
- The phrase "no evidence" is misleading because real truth-seeking is Bayesian and evidence updates priors rather than proving nullity.
- Declaring "no evidence" can be bad science communication when studies of varying quality exist.
