PEM Currents: The Pediatric Emergency Medicine Podcast Henoch–Schönlein Purpura (HSP)
Aug 8, 2023
Explore the intriguing world of Henoch–Schönlein Purpura, a common vasculitis affecting children. Discover the classic symptoms, including palpable purpura and abdominal pain. Learn about the challenges in diagnosis and the importance of supportive treatments. Delve into the nuances of managing this condition, including potential complications like nephritis. This concise discussion sheds light on vital monitoring practices for young patients.
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HSP Overview
- HSP is an IgA vasculitis affecting children aged 4-6, especially white and Asian males.
- It involves widespread IgA deposition in blood vessels, leading to palpable purpura below the belt line.
HSP Symptoms: Abdominal and Angioedema
- Abdominal pain is common, sometimes with bloody stools due to intussusception (2-6% of cases).
- Angioedema in gravity-dependent areas (legs, scrotum) can be an early sign.
HSP Complications
- Nephritis (kidney inflammation) occurs in 40% of HSP cases and can become chronic.
- Arthritis/arthralgia (joint pain) affects 75% of patients, typically in knees and ankles, but is non-deforming.