MedMaster by NURSING.com Bupropion (Wellbutrin)
Apr 7, 2023
Discover the uses and risks of Bupropion (Wellbutrin) - from treating depression and ADHD to its impact on dopamine and noradrenaline. Learn nursing considerations like seizure risk, mental status monitoring, and the importance of avoiding alcohol while taking bupropion.
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Bupropion's Neurotransmitter Action
- Bupropion increases dopamine and norepinephrine by inhibiting their reuptake in the synaptic cleft.
- This mechanism helps alleviate depression, support smoking cessation, and treat adult ADHD.
Bupropion Safety Precautions
- Do not administer bupropion to patients taking MAOIs; allow a 14-day gap between therapies.
- Monitor mental status closely due to seizure and suicidal ideation risks.
Bupropion Liver, Kidney, Alcohol Warning
- Exercise caution when administering bupropion in patients with liver or kidney impairment.
- Instruct patients to avoid alcohol to prevent seizures, hallucinations, anxiety, and panic attacks.