The Curbsiders Internal Medicine Podcast #301 LIVE! Top Pearls 2021: A Rapid Fire Review of Systems
Oct 25, 2021
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Shorter Antibiotic Courses Often Work
- Use shorter antibiotic courses for many common infections when clinically stable, often five days or less.
- Check clinical stability (improvement within 48 hours) before shortening therapy.
Amox-Clav Matches Fluoroquinolones For Diverticulitis
- For first-time uncomplicated diverticulitis, amoxicillin-clavulanate and ciprofloxacin+metronidazole had similar clinical outcomes.
- Amoxicillin-clavulanate had lower C. difficile rates in Medicare data.
Consider Observation For Uncomplicated Diverticulitis
- Consider observing well-appearing patients with uncomplicated diverticulitis instead of automatic antibiotics.
- If you treat, favor a lower-risk oral regimen like amoxicillin-clavulanate and discuss shared decision-making.