
Rheumnow Podcast
Ides of March (3.15.2024)
Mar 15, 2024
Exploring topics such as infections in patients on biologics, H. pylori infection and GI complications, IL-17 inhibitors and lupus management, vaccinations in rheumatology, and the impact of depression on all-cause mortality in RA patients.
22:26
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Quick takeaways
- Non-serious infections should not stop biologic treatments as they resolve with minimal impact.
- TNF inhibitors users in Japan face low NTM infection rates but need monitoring for adverse events.
Deep dives
Infections and Biologics: Serious vs. Non-Serious
Research on biologics highlighted a significant difference between non-serious and serious infections. Non-serious infections, such as upper respiratory tract infections, were significantly more common than serious infections, with the former recurring steadily over time. The study emphasized that non-serious infections should not prompt halting biologic treatments, as they resolve before the drug's effects. Additionally, recurrent non-serious infections may warrant further investigations to address underlying reasons.
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