In this engaging discussion, Alex Bangash, Founder of Transpose Platform and former CEO of Trusted Insight, shares his journey from engineering to venture capital. He highlights the evolving landscape of biotech investment and the pivotal role of limited partners. Alex explores how AI is revolutionizing both tech and life sciences, while emphasizing the unique challenges startup founders face today. With insights on modern entrepreneurship and the synergy between AI and biotech, he offers valuable guidance for navigating the future of venture capital.
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insights INSIGHT
Best Time to Be a Founder
Today is the most exciting time to be a founder due to abundant role models and drastically reduced capital needs.
AI is now the major accelerant, disrupting even traditionally resistant industries like hospitals.
insights INSIGHT
Silicon Valley’s Unique Startup Ecosystem
While innovation and resources exist globally, Silicon Valley still offers the best support and critical mass for startups.
AI advancements predominantly come from the Bay Area, which maintains an unmatched ecosystem for founders.
insights INSIGHT
AI's Growing Role in Biotech
AI is rapidly accelerating breakthroughs in biotech, especially in protein design and longevity research.
Though capital intensive, AI-driven medtech and biotech hold tremendous promise.
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Synopsis:
Venture capital is evolving, and so is biotech. In this episode of Biotech 2050, host Alok Tayi, CEO and co-founder of VibeBio, sits down with Alex Bangash, Founder of Transpose, an investment firm backing both startups and funds.
With over 20 years of experience in venture investing, Alex shares his unconventional journey from engineering to investing and how his unique perspective has shaped his approach to funding. He breaks down the shifting startup landscape, the critical role of LPs in biotech, and why AI is a game-changer for both tech and life sciences.
Alex also offers sharp insights into what it takes to build a successful venture fund today and the structural shifts that are redefining the industry. Whether you're a founder, investor, or biotech enthusiast, this episode is packed with valuable lessons on navigating the future of venture capital.
Biography:
Alex Bangash is the Founder of Transpose Platform, an anchor fund for the most disruptive venture funds of this decade. He is also the co-founder and former CEO of Trusted Insight, a machine learning–driven platform that hosts the world’s largest network of institutional investors. Prior to TI Platform, Alex managed capital for clients at premier endowments, foundations, family offices, insurance firms, sovereign wealth funds, and pension funds since 2003. He has helped invest over $2 billion in 50 funds with a track record of investing over $1 billion in 50+ funds for institutional investors with an IRR of 30%+ and a 2x NAV. He advised the first checks in Accel, First Round Capital, Founders Fund, Emergence, Y Combinator, Khosla, SaaStr, Initialized, Crystal Towers, and Baseline. Earlier in his career, Alex was an engineer and executive at AT&T, Lucent Technologies, Bell Labs, and GE. Alex holds an MBA from the Wharton School (where he is a frequent guest lecturer); an M.Eng. in Operations Research from Cornell, and a BS in Computer Science, English, and Economics from Cornell.
Biotech 2050 Podcast