GasGasGas - The FRCA Primary Exam Podcast Vivacast 16 - Misplacing 1000ml of circulating volume on the floor, Nerve conduction physiology, pH and acid base derangement
Apr 18, 2025
Delve into the physiological effects of sudden blood loss and how your body responds through baroreceptor reflexes and sympathetic activation. Explore the intricacies of nerve conduction, from resting membrane potential to the dynamics of action potentials. Learn about pH, acids, and the Henderson-Hasselbalch equation as they maintain acid-base balance. Finally, uncover the mystery of the anion gap and common causes of metabolic acidosis, plus exam tips for mastering your viva.
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Frame Blood Loss As Immediate/Intermediate/Delayed
- Structure answers into immediate, intermediate and delayed effects when asked about acute blood loss.
- Mention baroreceptor reflex, sympathetic response, ADH, RAAS, venoconstriction and fluid shifts across Starling forces.
Capacitance Vessels Help Restore Circulating Volume
- Venoconstriction and peripheral vasoconstriction mobilise blood from capacitance vessels to maintain preload.
- Renin–angiotensin–aldosterone and ADH then retain fluid and raise systemic vascular resistance for longer-term support.
Starling Forces Govern Rapid Fluid Refill
- Fluid shifts depend on capillary hydrostatic versus oncotic pressures governed by Starling forces.
- Reduced vascular hydrostatic pressure draws interstitial and intracellular fluid into the vascular space.