Big Technology Podcast

Brain Computer Interface Frontier: Movement, Coma, Depression, AI Merge

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Sep 3, 2025
Ben Rapoport and Michael Mager, co-founders of Precision Neuroscience, delve into the fascinating world of brain-computer interfaces (BCIs). They discuss using BCIs for revolutionizing stroke rehabilitation, decoding consciousness in coma patients, and treating depression with AI-driven neural biomarkers. The duo explores the potential to merge human cognition with machines, highlighting the ethical challenges and transformative possibilities. Their insights promise to change our understanding of the brain and reshape medical treatments.
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ANECDOTE

Forty Non‑Penetrating Implants Done

  • Precision has completed 40 temporary implants and enabled patients to control cursors and robotic arms without penetrating brain tissue.
  • That performance matched cutting-edge control yet avoided the tissue-damaging approach used by some other systems.
INSIGHT

High-Resolution Surface Recording

  • Precision records awake human brain activity at surface resolution previously unattainable using photolithography-made electrode arrays.
  • That high-resolution, non-damaging surface recording enables new decoding possibilities without penetrating neural tissue.
INSIGHT

Surface Coverage Scales Signal Bandwidth

  • Multiple non-penetrating modules can be used to scale electrode coverage up to thousands of channels across cortex.
  • Most conscious processing sits on the cortical surface, so covering that surface gives disproportionate access to behaviorally relevant signals.
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