Science Quickly What ‘Immortal’ Jellyfish and Famously Old Tortoises Tell Us about Aging
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Jun 11, 2025 João Pedro de Magalhães, Chair of molecular biogerontology at the University of Birmingham, dives into the fascinating world of aging science. He discusses unique creatures like the 'immortal' jellyfish and tortoises that defy typical lifespan expectations. The conversation explores evolutionary factors that influence longevity and the cutting-edge research tools aimed at uncovering genetic secrets behind aging. Magalhães raises intriguing possibilities for manipulating human aging based on insights from these remarkable animals.
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Extreme Variations in Lifespans
- Lifespans in the animal kingdom range from hours to centuries with huge variation even among similar species.
- Some creatures like certain jellyfish can biologically "reset" to younger forms, essentially avoiding aging.
Understanding Aging and Mortality
- Aging is a progressive physiological decline that increases vulnerability and decreases viability.
- A key pattern is that after about age 30, the chance of dying doubles approximately every eight years, seen also in animals but with different time scales.
Genetics Determine Aging Rates
- Aging rates differ vastly and are genetically encoded, not just due to environment or diet.
- Mice age roughly 20-30 times faster than humans intrinsically, highlighting genetic control over aging pace.