
 Big Technology Podcast
 Big Technology Podcast The Hidden Science Behind Brain-Computer Interfaces — With Sally Adee
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 Aug 27, 2025  Sally Adee, a science journalist and author of 'We Are Electric,' dives into the fascinating world of brain-computer interfaces (BCIs). She explores how electrical impulses drive our thoughts and movements, the groundbreaking potential of BCIs for disabled individuals, and the ethics surrounding pleasure-enhancing technology. Adee discusses innovative topics like limb regrowth in tadpoles, cancer cells that disrupt electrical balance, and the future challenges of keeping implants functional. Tune in for an electrifying journey through science and ethics! 
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Brain Signals Are Electrical
- Every thought and sensation is carried by electrochemical action potentials in neurons.
- Cell membrane voltage shifts (≈ -70 mV to 0 mV) enable rapid signaling for perception and movement.
Signal Count Drives BCI Capability
- Recording more neurons yields richer decoded intent and finer control for BCIs.
- Drilling into cortex with electrode arrays lets researchers deduce intended movement or speech from neural activity.
Neuralink Demonstration With Nolan Arbaugh
- Nolan Arbaugh used thought to move a cursor and trigger clicks after a Neuralink implant.
- He played and beat the host Alex Kantrowitz at a video-game demonstration of the BCI.

