Jason McLellan joins TWiV to reveal all we know about the SARS-CoV-2 spike protein, followed by Novavax and J&S phase 3 results and a discussion of variants of concern: neutralization by vaccine-induced antibodies, transmission, and virulence.

Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Rich Condit, and Amy Rosenfeld

Guest: Jason McLellan

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Links for this episode

Prefusion spike structure (Science)
Neutralization of VOC by vaccine induced antibodies: Moderna and Pfizer
Novavax COVID-19 vaccine phase 3 results (Novavax)
J&J COVID-19 vaccine phase 3 results (J&J)
B.1.1.7 has been in the US since November 2019 (virological.org)
NERVTAG report on B.1.1.7 virulence (pdf)
Timestamps by Jolene. Thanks!

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Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv

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