The Brian Lehrer Show HRT and the FDA
Jul 22, 2025
Jen Gunter, an OB/GYN and author known for her insightful work on women's health, dives into the hot topic of hormone replacement therapy. She discusses the FDA's proposal to remove warning labels, sparking a critical look at menopause and treatment options. Gunter clarifies the differences between vaginal estrogen and systemic therapies while addressing the personal success stories that shape treatment decisions. She also navigates the delicate balance of hormone therapy and breast cancer risks, urging the need for personalized assessments and careful evaluation of healthcare policies.
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Understanding Menopause Basics
- Menopause is the end of ovulation marked by one year without periods after age 45.
- Symptoms vary widely, including hot flashes, night sweats, brain fog, and vaginal dryness.
Vaginal vs Systemic Estrogen
- Vaginal estrogen treats local menopausal symptoms and is distinct from systemic estrogen therapy.
- Confusing the two leads to misunderstanding about safety and risk profiles.
Safety of Vaginal Estrogen
- Vaginal estrogen is a safe, low-risk local treatment supported by extensive observational data.
- Current black box warnings may scare patients and discourage use despite the safety profile.
