What is Cluster 5? Thanks for asking!

At the start of November, the World Health Organisation announced that six countries had reported COVID-19 cases in mink farms. These include Denmark, which is the world’s biggest producer of mink fur, the Netherlands, Spain, Sweden, Italy and the United States.This development led Denmark to take the radical decision of culling all 15 million minks in the country. The Prime Minister claimed a mutated strain of the virus, known as Cluster 5, had been transmitted back to humans, with 12 cases identified.

So where does this particular strain come from?

After spreading across the world, the coronavirus was transmitted from humans to minks. Its presence in these animals requires a mutation, which is how the Cluster 5 strain was created. And now the new strain has in turn been passed back to humans. According to the WHO, Cluster 5 has “moderately decreased sensitivity to neutralizing antibodies”, which could in theory threaten the effectiveness of a COVID-19 vaccine. Scientists believe the mutated strain of the virus was transmitted by farm workers to minks over the summer. During the mutation, it’s possible the spike protein of the virus changed, which is used to penetrate into human cells. Pharmaceutical companies seeking to develop a potential vaccine are mostly working on this particular protein. That includes the Pfizer vaccine, which the latest estimations have found to be effective in 90% of cases. There’s not yet any proof that this strain could scupper a vaccine, but the mutation identified means it’s theoretically possible.

If all those millions of minks have been culled, does that mean things are now under control? In under 3 minutes, we answer your questions!

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Rosamund Pike