First Schizophrenia Med in 30 Years, New Cell Type Discovered, and The Nine Planetary Boundaries
whatshot 4 snips
Sep 30, 2024
Exciting advancements in medicine are on the horizon! The FDA has approved Cobenfy, the first new schizophrenia medication in over 30 years, targeting cholinergic receptors for better treatment. A groundbreaking discovery of EndoMac progenitor cells in mice reveals their potential to enhance wound healing. Meanwhile, critical environmental boundaries are under threat, with six out of nine already crossed, highlighting urgent issues around climate change and biodiversity loss. The interconnectedness of these challenges calls for immediate action!
06:36
forum Ask episode
web_stories AI Snips
view_agenda Chapters
auto_awesome Transcript
info_circle Episode notes
insights INSIGHT
Cobenfy's Novel Approach
The FDA approved Cobenfy, a new schizophrenia drug targeting cholinergic receptors.
This differs from existing antipsychotics, which target dopamine receptors.
insights INSIGHT
EndoMac Progenitors
EndoMac progenitors, discovered in mice, can transform into blood vessel and immune cells.
This could revolutionize tissue repair, especially for conditions like diabetes.
insights INSIGHT
Planetary Boundaries Crossed
Humanity has crossed six of nine planetary boundaries, including climate change and biodiversity loss.
This risks irreversible environmental damage and threatens human civilization.
Get the Snipd Podcast app to discover more snips from this episode
In this episode of "Discover Daily," hosts Alex and Sienna explore groundbreaking advancements in medicine, cellular biology, and our understanding of Earth's planetary boundaries.
First, they discuss the FDA's approval of Cobenfy, the first new medication for schizophrenia in over three decades. This novel antipsychotic targets cholinergic receptors in the brain, offering a potentially more effective and tolerable treatment option for the millions of adults living with schizophrenia.
Next, the hosts dive into the discovery of EndoMac progenitors, a new type of cell found in adult mice that can transform into both blood vessel cells and immune cells. These unique cells show remarkable abilities to enhance wound healing, particularly in conditions like diabetes where healing is often impaired. The discovery of EndoMac progenitors, predicted by scientists over a century ago, could open up exciting new avenues for regenerative medicine and tissue repair.
Finally, Alex and Sienna take an in-depth look at the concept of planetary boundaries, the environmental limits within which humanity can safely operate. A recent analysis found that six out of nine of these boundaries have now been crossed, including those for climate change, biodiversity loss, and land-system change. The hosts explain the interconnected nature of these boundaries and discuss the urgent need for transformative action to reduce human impacts on critical Earth systems. They explore the implications for the average person and highlight the importance of understanding these limits for guiding humanity towards a more sustainable future.
Perplexity is the fastest and most powerful way to search the web. Perplexity crawls the web and curates the most relevant and up-to-date sources (from academic papers to Reddit threads) to create the perfect response to any question or topic you’re interested in.
Take the world's knowledge with you anywhere. Available on iOS and Android
Join our growing Discord community for the latest updates and exclusive content.
Discover Daily by Perplexity