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Healio Rheuminations

COVID-19, long COVID and the rheumatologist with Leonard Calabrese, DO

Jan 4, 2024
Discussing COVID-19, long COVID, and the role of rheumatologists in 2023. Understanding vaccine responses in immunocompromised patients and the Lancet Rheumatology MELODY study. Exploring long COVID symptoms and post-COVID conditions. Delving into autoimmune responses, therapeutic strategies, and the need for individualized treatment approaches.
29:04

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Quick takeaways

  • Immunocompromised patients on anti-CD 20 therapy may have insufficient antibody responses post-vaccination.
  • Long COVID presents challenges due to varied definitions, impacting patients with persistent symptoms like fatigue and pain.

Deep dives

Overview of COVID-19 Status and Vaccine Responses

The COVID-19 pandemic has led to a significant transformation in medical understanding, causing what is termed 'epistemic chaos.' With the evolution of variants like Delta and Omicron, new mutations such as the JN1 variant are emerging, impacting areas like Cleveland, Ohio, with a surge of COVID cases. Studies indicate that some immunocompromised patients may not generate sufficient antibody responses post-vaccination, particularly those on anti-CD 20 therapy.

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