Freely Filtered 025: Making sense of albuminuria, proteinuria, and the dipstick

The Filtrate:

Matt Sparks

Joel Topf

Swapnil Hiremath

Jennie Lin

Jordy Cohen

And two special guests:

Morgan Grams, study author.

Talar Kharadjian, nephrology fellow UC San Diego

Show Notes:

History of albuminuria from Matt’s opening monolog: https://academic.oup.com/ndt/article/18/7/1281/1809803

Microalbuminuria As A Predictor Of Clinical Nephropathy In Insulin-Dependent Diabetes Mellitus in the Lancet 1982.

Microalbuminuria Predicts Clinical Proteinuria and Early Mortality in Maturity-Onset Diabetes in the NEJM 1984

Episode of Freely Filtered with Dr. Feldman, the big guy at the top of the CRIC trial: NSAIDs vs Opioids.

The Aldo study where they didn’t do a meta-analysis but they should have: Aldosteronism is everywhere.

Estimating Urine Albumin-to-Creatinine Ratio from Protein-to-Creatinine Ratio: Development of Equations using Same-Day Measurements. Canadian data. CJASN

The kidney failure risk equation has a dotcom: https://kidneyfailurerisk.com

KDIGO Controversies Conference on Early Identification & Intervention in CKD

Choose Your Own Adventure: Cave of Time.

Witte et al. in 2009 JASN on first morning urine vs 24 hour collection: First Morning Voids Are More Reliable Than Spot Urine Samples to Assess Microalbuminuria

Sensitivity and specificity for Joel to study

Your Manuscript On Peer Review

Nephrology Business Leaders University (NBLU)

Cloth Masks May Prevent Transmission of COVID-19: An Evidence-Based, Risk-Based Approach with lead author Catherine Clase

https://www.clothmasks.ca

Elimination or Prolongation of ACE Inhibitors and ARB in Coronavirus Disease 2019 (REPLACECOVID)

Fast Grant. Apparently they are not just for Brian Byrd

NephJC ACE2 Stuff as Jordy calls it: http://www.nephjc.com/news/covidace2

The BRACE-CORONA trial a 700 person RCT of ACEi and ARB in Covid-19. No effect. Tweet stream by Swapnil.

MC Hammer is a science nerd: https://cen.acs.org/education/science-communication/Hammer-time-Science-Twitter-drummers/98/i31

Hammerman origin story for the MC Hammer cartoon.

Bowman Society Lecture - Race & Renal Function Calculations

Basic Research Forum for Emerging Kidney Scientists: A Partnership Between APS and ASN