Death by Neurologic Criteria
Jul 14, 2022
Dr. David Greer, a leading neurologist and chair of the neurology department at Boston University, delves into the crucial topic of brain death. He explains the World Brain Death Project's goals to standardize brain death determination practices. Interesting discussions include the challenges of accurately determining brain death, the importance of detailed clinical examinations, and the role of ancillary testing. Dr. Greer emphasizes the need for meticulousness and conservative approaches in these life-and-death decisions, making it vital for clinicians to familiarize themselves with best practices.
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Global Standards Reduce Diagnostic Variability
- The World Brain Death Project sets conservative minimum criteria to standardize global brain death determinations.
- Minimum criteria are designed to avoid false positives by demanding thorough, irreversible evidence.
Confirm Cause And Exclude Confounders
- Verify the cause of coma and confirm irreversibility before any brain death testing.
- Exclude confounders like sedatives, paralytics, metabolic problems, hypothermia, and intoxication first.
Follow The Two Pillars Of Clinical Testing
- Perform a detailed neurologic exam and an apnea test as the two clinical pillars.
- Confirm coma, absence of brainstem reflexes, and absent medullary respiratory drive.



